Connect Upstream – The first fully integrated upstream platform

Integrated Upstream Platform -
From Cell Line to Manufacturing

Sartorius Stedim Biotech has developed the first fully integrated upstream platform. It connects a top-performing expression system with outstanding equipment and process control for the rapid development and scale-up of robust, high-titer commercial manufacturing processes.

 
 

Speed to Clinic

Reaching the clinical phase as quickly as possible is crucial. By combining the right tools and testing services, you'll develop your cell lines and processes in the fastest and most cost-effective way.

Reach the clinic faster

 

 

 

Increased Titers

Optimize your process for high titers to move on quickly to clinical trials. The unique CHOptimizer® solution helps you find the best media mixture, optimal process parameters and a successful feed strategy.

Increase your titers

 

Quality by Design

Optimal transitions between scales are essential from cell line to commercial manufacturing. With the right QbD strategy, you'll achieve robust, high-performing and retrievable processes.

Improve QbD

 

Robust Production

For long-term robust production, you'll need flexible and cost-effective biomanufacturing platforms. Our Integrated Solutions team will design, deliver and implement them for you – with unmatched expertise.

Build robust processes

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"Our upstream platform
connects outstanding process
technologies and brings biology
to single-use bioprocessing."

 

 

Stefan Schlack,
Senior Vice President, Marketing & Product Management Bioprocess Solutions

News

Free On-Demand Webinar: Speed to Clinic
(2017-07-24)

Learn more about how time can be saved during process development providing you with greater speed to clinic. Our webinar is available for you to view on-demand – for free.

Standard Disposables Design™ (SDD™)
(2017-07-20)

Buffer and media preparation are common in the production of antibody and proteinbased therapeutics, antibiotics, and vaccines. So the Standard Disposables Design™ (SDD™) initiative has been launched to concentrate on standardizing disposables for these applications. Read about PM Group’s vision to have most major biopharmaceutical companies store their media and buffers in the same design of disposable bags.

Raising the Bar for Upstream Processing
(2017-07-19)

Read this conversation with Stefan Schlack and Christel Fenge to learn about current market trends. Our experts summarize the key themes of our last European Upstream and Downstream Forum and talk about how our upstream solutions support customers, from concept to commercial production, to accelerate product development and scale-up.

Active Dashboard 2 Allows Easy Access to Process Performance Data
(2017-07-17)

We have launched the Active Dashboard 2, an advanced software solution. Delivering in-depth insights into process performance across the manufacturing network, the release helps managerial staff to achieve better timely decisions, ensuring superior manufacturing success. Read more about the benefits of the Active Dashboard 2 in our product news.

New Tools for Optimizing Custom Media Design
(2017-07-14)

At last year's European Upstream & Downstream Technology Forum, Michael Gillmeister presented independent case studies of a media optimization program offered jointly by Lonza and Sartorius Stedim Biotech. The program uses an ambr® 15 microbioreactor system to generate custom media that are chemically defined and contain no products of animal origin.

New Generation of Single-Use Bioreactors Can Reduce Bioprocess Development Time and Cost
(2017-07-11)

Our new BIOSTAT STR® bioreactor range featuring upgraded hardware and software, as well as a fully integrated, new design of Flexsafe STR® single-use bags, ensures quick and easy bioprocess scale-up of biologics and vaccines. Read the full SelectScience® article:

What Is the Best Way to Approach Biosimilar Development?
(2017-07-10)

To demonstrate biosimilarity it is essential that the biological product has been proven to be highly similar to the originator product and has no clinically meaningful differences in terms of its safety and efficacy. Read this blog entry to learn about the best practices for biosimilar development.

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Your Guide to Upstream Processing Solutions

Upstream Catalog

Whether you just need a bioreactor or a single-use bag for media storage or are looking for a partner to build your completely single-use manufacturing facility, we will provide you with all the options, services and support you need.Our comprehensive upstream catalog consists of six chapters detailing our product portfolio throughout the upstream process. The catalog is dedicated to our cell line development services, media,  bioreactors and fermenters, clarification solutions, analytics and engineering services.Download the digitally optimized catalog as a PDF directly on your computer, tablet or smartphone.

Download upstream catalog

Addressing the Challenges of Developing Biopharmaceutical Drugs

by Stefan Schlack, 2016

The biopharmaceutical industry has enjoyed considerable success; however, there are strong signs this market is becoming increasingly competitive.

Stefan Schlack, Senior Vice President of Marketing & Product Management at Sartorius Stedim Biotech, shares his analysis of the industry as it stands in 2016 and offers solutions to the challenges the biopharmaceutical companies face.

Download article

Contact

Reduce your time to market and learn more about Sartorius Stedim Biotech’s unique integrated upstream platform. Let us know your questions and requests. You will hear from us shortly. For job enquiries, please visit our Careers page.

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Total Solutions Support the Growth of a Dynamic Industry

Caine & Montgomery (2014) BPI 12(8) Sept. 23, 2014

In this interview with the team from BioProcess International, Reinhard Vogt (Executive Vice President of Marketing, Sales & Services, Executive Board member, Sartorius Stedim Biotech) and Stefan Schlack (Senior Vice President, Marketing & Product Management, Sartorius Stedim Biotech) discuss the need to move away from focusing on components and individual products and instead offer complete single-use solutions.

Reinhard Vogt: “Single-use technologies have reached a quality level similar to stainless steel”
Stefan Schlack: “Our industry faces four key challenges: capacity adaptation, smart process transfers, risk mitigation, and cost savings.”

The company’s recent acquisitions, together with its chemometrics offering, lay the foundation for QbD approaches as well as effective process optimization and characterization in a very short time frame and demonstrate the benefits of connecting upstream technologies.

Download BPI article

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Events with Sartorius Stedim Biotech

Check here for events, conferences, trade fairs and more in your country. Just click on the icons of the continents for more information.

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Connect Upstream: The fully integrated process platform

December 1-2, 2016
ETIF
Buenos Aires, Argentina

Connect Upstream: The fully integrated process platform

February 27 - March 2, 2017
BioProcess International West
San Francisco, CA, USA

February 27 - March 2, 2017
IFPAC Annual Meeting 2017
North Bethesda, MD, USA

March 7-8, 2017
2017 ISPE Aseptic Conference
Reston, VA, USA

March 14, 2017
Life Sciences Technology Conference
Raleigh, NC, USA

April 2-6, 2017
253rd ACS National Meeting & Exposition
San Francisco, CA, USA

April 3-5, 2017
2017 PDA Annual Meeting
Anaheim, CA, USA

May 1-5, 2017
PEGS – The Essential Protein & Antibody Engineering Summit
Boston, MA, USA

May 23-24, 2017
Cell Culture World Congress USA 2017
San Diego, CA, USA

May 23-24, 2017
World Biosimilar Congress USA 2017
San Diego, CA, USA

June 5-7, 2017
Cell Line Development & Engineering
San Diego, CA, USA

June 14-17, 2017
ISSCR 2017 Annual Meeting
Boston, MA, USA

August 13-17, 2017
Precision & Performance with Measurement Science
National Harbor, MD, USA

August 21-25, 2017
Bioprocessing Summit
Boston, MA, USA

September 20-22, 2017
World ADC San Diego
Sand Diego, CA, USA

September 25-28, 2017
BioProcess International Conference & Exhibition
Boston, MA, USA

October 4, 2017
ISPE Boston
Boston, MA, USA

October 29 - November 1, 2017
2017 ISPE Annual Meeting
San Diego, CA, USA

October 29 - November 1, 2017
RAFT – Recent Advances in Fermentation Technology
Bonita Springs (Ft. Myers), FL, USA

Connect Upstream: The fully integrated process platform

February 22-23, 2017
Research Xchange Forum
Goettingen, Germany

April 3-6, 2017
ISPE 2017 Europe Annual Conference
Barcelona, Spain

April 25-26, 2017
BioProcess International European Summit
Amsterdam, The Netherlands

April 25-27, 2017
Viral Safety & Raw Materials
Amsterdam, The Netherlands

May 14-17, 2017
25th ESACT Meeting
Lausanne, Switzerland

September 17-21, 2017
ECI: Integrated Continuous Biomanufacturing III
Cascais, Portugal

October 31 - November 2, 2017
European Antibody Congress 2017
Basel, Switzerland

November 7-8, 2017
Universe of Pre-filled Syringes & Injection Devices
Vienna, Austria

November 21-24, 2017
Pharmtech
Moscow, Russia

Connect Upstream: The fully integrated process platform

March 12-14, 2017
14th China Association of Clinical Laboratory Practice (Intl.) Spring Expo
Qingdao, China

March 14, 2017
Sartorius Stedim Biopharma Forum 2017
Bangalore, India

March 17, 2017
Sartorius Stedim Biopharma Forum 2017
Mumbai, India

April 19-21, 2017
CIPM – China International Pharmaceutical Machinery Exposition
Qingdao, China

April 26-27, 2017
4th Pathogen Clean Asian Forum
Shanghai, China

June 20-22, 2017
CPHI China 2017
Shanghai, China

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